Spastic paraplegia four (SPG4; often known as SPAST-HSP) is characterized by insidiously progressive bilateral reduce-limb gait spasticity. More than 50% of affected men and women have some weak spot while in the legs and impaired vibration sense with the ankles.안전하고 신뢰할 수 있는 정보: 검증된 정보만 제공하여 안심하고